岳永康,男,1992年生。理学博士,副教授,博士研究生导师,山西省优青,山西省高校优秀青年学术带头人。2013年7月毕业于忻州师范学院,获理学学士学位。2018年7月毕业于山西大学分子科学研究所,获理学博士学位,留所工作。
主要研究方向:
荧光染料与生物成像
主持科研项目:
1. 山西省优秀青年基金(25万元,202303021224003,2024.1——2026.12)
2. 国家自然科学基金面上项目(54万元,22277069,2023.1——2026.12)
3. 国家自然科学基金青年科学基金项目(26万元,21907062,2020.1——2022.12)
4. 山西省高校优秀青年学术带头人(20万元,2019,2019.9——2022.9)
5. 山西省高等学校科技创新项目(3万元,2019L0031,2019.9——2022.9)
代表性论文:
1. Yongkang Yue, Tingting Zhao, Zhou Xu, Weijie Chi, Xiaojun Chai, Jiahong Ai, Jiawei Zhang, Fangjun Huo, Robert M. Strongin, Caixia Yin*, Enlarging the Stokes shift by weakening the p-conjugation of cyanines for high signal-to-noise ratiometric imaging, Adv. Sci., 2023, 2205080.
2. Yongkang Yue, Tingting Zhao, Kaiqing Ma, Fangjun Huo, Caixia Yin*, Endogenous cysteine fluorescence monitoring and its deployment in tumour demarcation, Chem. Commun., 2022, 58, 2311−2314.
3. Yongkang Yue, Tingting Zhao, Yuting Wang, Kaiqing Ma, Xingkang Wu, Fangjun Huo, Fangqin Cheng, Caixia Yin*, HSA-Lys-161 covalent bound fluorescent dye for in vivo blood drug dynamic imaging and tumor mapping, Chem. Sci., 2022, 13, 218−224.
4. Kaiqing Ma,# Yongkang Yue,# Lingling Zhao, Jianbin Chao, Caixia Yin*, A sequentially activated bioluminescent probe for observation of cellular H2O2 production induced by cysteine, Chem. Commun., 2021, 57, 10015-10018.
5. Yongkang Yue, Fangjun Huo, Caixia Yin*, The chronological evolution of small organic molecular fluorescent probes for thiols, Chem. Sci., 2021, 12, 1220−1226.
6. Yongkang Yue, Fangjun Huo, Yuting Wang, Kaiqing Ma, Xiaoqing Li, Caixia Yin*, Mutual correlation evaluation of Cys and Hcy in serum through reaction activity regulated fluorescence quantification, Chem. Commun., 2020, 56, 9146−9149.
7. Yongkang Yue, Fangjun Huo, Xueying Pei, Yuting Wang, Caixia Yin*, Fluorescent imaging of resveratrol induced subcellular cysteine upregulation, Anal. Chem., 2020, 92, 6598−6603.
8. Yongkang Yue, Fangjun Huo, Fangqin Cheng, Xijing Zhu, Tendai Mafireyi, Robert M. Strongin*, Caixia Yin*, Functional synthetic probes for selective targeting and multi-analyte detection and imaging, Chem. Soc. Rev., 2019, 48, 4155−4177. (ESI高被引论文)
9. Yongkang Yue, Fangjun Huo, Caixia Yin*, Noradrenaline specific, efficient visualization in brain tissue triggered by unique ‘cascade’ nucleophilic substitution, Anal. Chem., 2019, 91, 2255−2259.
10. Yongkang Yue#, Fangjun Huo#, Ping Yue, Xiangming Meng, James C. Salamanca, Jorge O. Escobedo, Robert M. Strongin, Caixia Yin*, In situ lysosomal cysteine-specific targeting and imaging during dexamethasone induced apoptosis, Anal. Chem., 2018, 90, 7018−7024.
11. Yongkang Yue#, Fangjun Huo#, Peng Ning, Yongbin Zhang, Jianbin Chao, Xiangming Meng*, Caixia Yin*, Dual-site fluorescent probe for visualizing the metabolism of Cys in living cells, J. Am. Chem. Soc., 2017, 139, 3181−3185. (ESI高被引论文)
12. Yongkang Yue#, Fangjun Huo#, Xiaoqi Li, Ying Wen, Tao Yi*, James Salamanca, Jorge O. Escobedo, Robert M. Strongin*, Caixia Yin*, pH-Dependent fluorescent probe that can be tuned for cysteine or homocysteine, Org. Lett., 2017, 19, 82−85.
13. 岳永康, 霍方俊, 阴彩霞*, 硫醇亲核反应及其荧光识别研究, 中国科学: 化学, 2016, 47, 249–257.
14. Yongkang Yue, Fangjun Huo, Jianbin Chao, Yongbin Zhang, Ramón Martínez-Máñez*, Caixia Yin*, Curcumin-based “Enhanced SNAr” promoted ultrafast fluorescent probe for thiophenols detection in aqueous solution and in living cells, Anal. Chem., 2016, 88, 10499−10503.
15. Yongkang Yue, Fangjun Huo, Songyi Lee, Caixia Yin*, Juyoung Yoon*, Jianbin Chao, Yongbin Zhang, Fangqin Cheng*, A dual colorimetric/fluorescence system for determining pH based on the nucleophilic addition reaction of an o-hydroxymerocyanine dye, Chem. Eur. J., 2016, 22, 1239−1243.
联系方式:
地址:太原市坞城路92号
单位:山西大学分子科学研究所
邮编:030006
E-mail:ykyue@sxu.edu.cn