张洪星，男，1988年生，黑龙江绥化人，理学博士，硕士生导师。长期从事荧光染料及荧光探针的开发，主要研究兴趣为新型荧光染料的合成、活性硫化物（ROS）和活性氧/氮化物（ROS/RNS）的传感及生物影像研究，以第一作者身份在国际著名期刊JACS, Chem. Sci., Biomaterials, Chem. Commun.共发表SCI论文5篇。

学习与工作经历：

2018/07 – 至今，山西大学，化学化工学院，讲师

2015/09 – 2018/07，山西大学，博士

2012/09 – 2015/07，山西大学，硕士

2008/09 – 2012/07，山西大学，学士

讲授课程：有机化学

研究方向：分子识别与生物传感

主持科研项目：

1、国家自然科学基金青年科学基金，2021.01-2023.12，卤线粒体靶向的水溶性“碳-双吡咯甲烷（Carbodipy）”正离子型荧光染料的设计、合成、光物理性质研究以及在肿瘤光动力治疗方面的应用，主持

2、山西省高等学校创新人才支持计划，2019-2021，主持

代表性论文：

1. Hongxing Zhang, Jing Liu*, Yuanqiang Sun, Mengxing Liu and Wei Guo*, Carbon–Dipyrromethenes: Bright Cationic Fluorescent Dyes and Potential Application in Revealing Cellular Trafficking of Mitochondrial Glutathione Conjugates, J. Am. Chem. Soc. 2020, 40, 17069-17078.

2. Hongxing Zhang, Jing Liu, Bo Hu, Linfang Wang, Z Yang, Xu Han, Juanjuan Wang, Wei Bai, Wei Guo*, Dual-Channel Fluorescence Diagnosis of Cancer Cells/Tissues Assisted by OATP Transporters and Cysteine/Glutathione, Chemical Science, 2018, 9, 3209.

3. Hongxing Zhang, Jing Liu, Linfang Wang, Minjia Sun, Xiaohan Yan, Juanjuan Wang, Jianping Guo, Wei Guo*, Amino-Si-rhodamines: A new class of two-photon fluorescent dyes with intrinsic targeting ability for lysosomes, Biomaterials, 2018, 158, 10.

4. Hongxing Zhang, Jing Liu, Chenlu Liu, Pengcheng Yu, Minjia Sun, Xiaohan Yan, Jian-Ping Guo*, Wei Guo,* Imaging lysosomal highly reactive oxygen species and lighting up cancer cells and tumors enabled by a Si-rhodamine-based near infrared fluorescent probe, Biomaterials, 2017, 133, 60.

5. Hongxing Zhang, Jing Liu, Yuan-Qiang Sun, Yingying Huo, Yaohua Li, Weizhi Liu, Xiao Wu, Nishu Zhu, Yawei Shi and Wei Guo*, A mitochondria-targetable fluorescent probe for peroxynitrite: fast response and high selectivity, Chem. Commun., 2015, 51, 2721.